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1

Molecular mechanisms of regulation of HTLV-1 gene expression and its association with leukemogenesis

Yoshida, Mitsuaki, Inoue, Junichiro, Fujisawa, Junichi, Seiki, Motoharu

Journal:

Year:

1989

Language:

english

File:

PDF, 529 KB

english, 1989

2

Unique Biological Activity and Potential Role of Monomeric Laminin-γ2 as a Novel Biomarker for Hepatocellular Carcinoma: A Review

Yasuda, Hiroshi, Nakagawa, Masatoshi, Kiyokawa, Hirofumi, Yoshida, Eisaku, Yoshimura, Toru, Koshikawa, Naohiko, Itoh, Fumio, Seiki, Motoharu

Journal:

International Journal of Molecular Sciences

Year:

2019

File:

PDF, 11.11 MB

2019

3

Activation of the precursor of gelatinase A/72 kda type IV collagenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase (MT-MMP) and with lymph node metastasis

Masato Tokuraku, Hiroshi Sato, Sinya Murakami, Yasunori Okada, Yoh Watanabe, Motoharu Seiki

Journal:

International Journal of Cancer

Year:

1995

Language:

english

File:

PDF, 871 KB

english, 1995

4

Serum Monomeric Laminin-Î"2 as a Novel Biomarker for Hepatocellular Carcinoma

Kiyokawa, Hirofumi, Yasuda, Hiroshi, Okuse, Chiaki, Matsumoto, Nobuyuki, Yoshimura, Toru, Yoshida, Eisaku, Nakagawa, Masatoshi, Seiki, Motoharu, Koshikawa, Naohiko, Itoh, Fumio

Journal:

Gastroenterology

Year:

2017

Language:

english

File:

PDF, 487 KB

english, 2017

5

Different metastatic potentials of ras- and src-transformed BALB/c 3T3 A31 variant cells

Masaaki Tatsuka, Takahide Ota, Nobuyuki Yamagishi, Yasunari Kashihara, Morimasa Wada, Naoki Matsuda, Hiromi Mitsui, Motoharu Seiki, Shizuo Odashima

Journal:

Molecular Carcinogenesis

Year:

1996

Language:

english

File:

PDF, 887 KB

english, 1996

6

Impaired alveolization in mice deficient in membrane-type matrix metalloproteinase 1 (MT1-MMP)

Kazuharu Irie, Kiyoshi Komori, Motoharu Seiki, Eichi Tsuruga, Yasunori Sakakura, Tohru Kaku, Toshihiko Yajima

Journal:

Medical Molecular Morphology

Year:

2005

Language:

english

File:

PDF, 504 KB

english, 2005

7

High throughput analysis of proteins associating with a proinvasive MT1-MMP in human malignant melanoma A375 cells

Taizo Tomari, Naohiko Koshikawa, Takayuki Uematsu, Takashi Shinkawa, Daisuke Hoshino, Nagayasu Egawa, Toshiaki Isobe, Motoharu Seiki

Journal:

Year:

2009

Language:

english

File:

PDF, 1.68 MB

english, 2009

8

Identification of proteins that associate with integrin α2 by proteomic analysis in human fibrosarcoma HT-1080 cells

Takayuki Uematsu, Chieko Konishi, Daisuke Hoshino, Xiao Han, Taizo Tomari, Nagayasu Egawa, Yoshikazu Takada, Toshiaki Isobe, Motoharu Seiki, Naohiko Koshikawa

Journal:

Journal of Cellular Physiology

Year:

2012

Language:

english

File:

PDF, 662 KB

english, 2012

9

Calmodulin antagonists increase the expression of membrane-type-1 matrix metalloproteinase in human uterine cervical fibroblasts

Akira Ito, Miwako Yamada, Takashi Sato, Kyoko Sanekata, Hiroshi Sato, Motoharu Seiki, Hideaki Nagase, Yo Mori

Journal:

Year:

1998

Language:

english

File:

PDF, 287 KB

english, 1998

10

Induction and stimulation of 92-kDa gelatinase / type IV collagenase production in osteosarcoma and fibrosarcoma cell lines by tumor necrosis factor α

Yasunori Okada, Hiroyuki Tsuchiya, Hirokazu Shimizu, Katsuro Tomita, Isao Nakanishi, Hiroshi Sato, Motoharu Seiki, Kyoko Yamashita, Taro Hayakawa

Journal:

Biochemical and Biophysical Research Communications

Year:

1990

Language:

english

File:

PDF, 1.00 MB

english, 1990

11

Control and inhibition analysis of complex formation processes

Takashi Saitou, Keiko Itano, Daisuke Hoshino, Naohiko Koshikawa, Motoharu Seiki, Kazuhisa Ichikawa, Takashi Suzuki

Journal:

Theoretical Biology and Medical Modelling

Year:

2012

Language:

english

File:

PDF, 682 KB

english, 2012

12

[Part 1: Biological Sciences] || Human Adult T-Cell Leukemia Virus: Complete Nucleotide Sequence of the Provirus Genome Integrated in Leukemia Cell DNA

Motoharu Seiki, Seisuke Hattori, Yoko Hirayama and Mitsuaki Yoshida

Journal:

Proceedings of the National Academy of Sciences

Year:

1983

Language:

english

File:

PDF, 1.06 MB

english, 1983

13

Development of a fully automated chemiluminescence immunoassay for urine monomeric laminin-γ2 as a promising diagnostic tool of non-muscle invasive bladder cancer

Nakagawa, Masatoshi, Karashima, Takashi, Kamada, Masayuki, Yoshida, Eisaku, Yoshimura, Toru, Nojima, Masanori, Inoue, Keiji, Shuin, Taro, Seiki, Motoharu, Koshikawa, Naohiko

Journal:

Biomarker Research

Year:

2017

Language:

english

File:

PDF, 768 KB

english, 2017

14

Flow injection analysis for measurement of activity of matrix metalloproteinase-7 (MMP-7)

Michiyasu Itoh, Mamoru Osaki, Tadashige Chiba, Kazuto Masuda, Toshifumi Akizawa, Masanori Yoshioka, Motoharu Seiki

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

1997

Language:

english

File:

PDF, 706 KB

english, 1997

15

Nonspecific integration of the HTLV provirus genome into adult T-cell leukaemia cells

Seiki, Motoharu, Eddy, Roger, Shows, Thomas B., Yoshida, Mitsuaki

Journal:

Year:

1984

File:

PDF, 473 KB

1984

16

Characterization of a truncated recombinant form of human membrane type 3 matrix metalloproteinase

Taketoshi Shimada, Hiroyuki Nakamura, Eiko Ohuchi, Yutaka Fujii, Yasushi Murakami, Hiroshi Sato, Motoharu Seiki, Yasunori Okada

Journal:

Year:

1999

Language:

english

File:

PDF, 514 KB

english, 1999

17

The second pX product p27x-III of HTLV-1 is required for gag gene expression

Jun-ichiro Inoue, Motoharu Seiki, Mitsuaki Yoshida

Journal:

Year:

1986

Language:

english

File:

PDF, 348 KB

english, 1986

18

Membrane-type matrix metalloproteinase-1(MT1-MMP) gene is overexpressed in highly invasive hepatocellular carcinomas

Tomika Harada, Shigeki Arii, Masahiro Mise, Takashi Imamura, Hiroaki Higashitsuji, Masaharu Furutani, Mototaka Niwano, Shun-ichi Ishigami, Manabu Fukumoto, Motoharu Seiki, Hiroshi Sato, Masayuki Imamu

Journal:

Journal of Hepatology

Year:

1998

Language:

english

File:

PDF, 318 KB

english, 1998

19

MT1-MMP-Dependent Control of Skeletal Stem Cell Commitment via a β1-Integrin/YAP/TAZ Signaling Axis

Tang, Yi, Rowe, R. Grant, Botvinick, Elliot L., Kurup, Abhishek, Putnam, Andrew J., Seiki, Motoharu, Weaver, Valerie M., Keller, Evan T., Goldstein, Steven, Dai, Jinlu, Begun, Dana, Saunders, Thomas,

Journal:

Developmental Cell

Year:

2013

Language:

english

File:

PDF, 4.53 MB

english, 2013

20

TWO-STEP SANDWICH ENZYME IMMUNOASSAY USING MONOCLONAL ANTIBODIES FOR DETECTION OF SOLUBLE AND MEMBRANE- ASSOCIATED HUMAN MEMBRANE TYPE 1-MATRIX METALLOPROTEINASE

Aoki, Takanori, Yonezawa, Kayoko, Ohuchi, Eiko, Fujimoto, Noboru, Iwata, Kazushi, Shimada, Taketoshi, Shiomi, Takayuki, Okada, Yasunori, Seiki, Motoharu

Journal:

Journal of Immunoassay and Immunochemistry

Year:

2002

Language:

english

File:

PDF, 198 KB

english, 2002

21

VIP36 protein is a target of ectodomain shedding and regulates phagocytosis in macrophage raw 264.7 cells.:

Shirakabe, Kyoko, Hattori, Seisuke, Seiki, Motoharu, Koyasu, Shigeo, Okada, Yasunori

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 576 KB

english, 2014

22

Cell Adhesion in Cancer

Oh, Eok-Soo, Seiki, Motoharu, Gotte, Martin, Chung, Jun

Journal:

International Journal of Cell Biology

Year:

2012

Language:

english

File:

PDF, 34 KB

english, 2012

23

c-Jun, c-Fos and Their Family Members Activate the Transcription Mediated by Three 21-bp Repetitive Sequences in the HTLV-I Long Terminal Repeat

Fujii, Masahiro, Tsuchiya, Haruo, Meng, Xiao-Bo, Seiki, Motoharu

Journal:

Year:

1995

Language:

english

File:

PDF, 1.74 MB

english, 1995

24

Experimental Metastasis of Oncogene-transformed NIH 3T3 Cells in Chick Embryo

Yoshio Endo, Motoharu Seiki, Hiroyuki Uchida, Mika Noguchi, Yuri Kida, Hiroshi Sato, Masayoshi Mai, Takuma Sasaki

Journal:

Year:

1992

File:

PDF, 457 KB

1992

25

Ursolic acid-induced down-regulation of MMP-9 gene is mediated through the nuclear translocation of glucocorticoid receptor in HT1080 human fibrosarcoma cells

Cha, Hee-Jae, Park, Moon-Taek, Chung, Hae-Young, Kim, Nam Deuk, Sato, Hiroshi, Seiki, Motoharu, Kim, Kyu-Won

Journal:

Year:

1998

Language:

english

File:

PDF, 580 KB

english, 1998

26

[Part 1: Biological Sciences] || Human Adult T-Cell Leukemia Virus: Molecular Cloning of the Provirus DNA and the Unique Terminal Structure

Motoharu Seiki, Seisuke Hattori and Mistuaki Yoshida

Journal:

Proceedings of the National Academy of Sciences

Year:

1982

Language:

english

File:

PDF, 1.13 MB

english, 1982

27

The ERK signaling target RNF126 regulates anoikis resistance in cancer cells by changing the mitochondrial metabolic flux

Yoshino, Seiko, Hara, Toshiro, Nakaoka, Hiroki J, Kanamori, Akane, Murakami, Yoshinori, Seiki, Motoharu, Sakamoto, Takeharu

Journal:

Year:

2016

Language:

english

File:

PDF, 5.85 MB

english, 2016

28

Detection of the Heterogeneous O-Glycosylation Profile of MT1-MMP Expressed in Cancer Cells by a Simple MALDI-MS Method

Shuo, Takuya, Koshikawa, Naohiko, Hoshino, Daisuke, Minegishi, Tomoko, Ao-Kondo, Hiroko, Oyama, Masaaki, Sekiya, Sadanori, Iwamoto, Shinichi, Tanaka, Koichi, Seiki, Motoharu, Karamanos, Nikos K.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.34 MB

english, 2012

29

Expression of type-IV collagenases in human tumor cell lines that can form liver colonies in chick embryos

Yuri Tsuchiya, Yoshio Endo, Hiroshi Sato, Yasunori Okada, Masayoshi Mai, Takuma Sasaki, Motoharu Seiki

Journal:

International Journal of Cancer

Year:

1994

Language:

english

File:

PDF, 2.11 MB

english, 1994

30

Identification of CD44 as a cell surface marker for Müller glia precursor cells

Toru Shinoe, Hiroshi Kuribayashi, Hideyuki Saya, Motoharu Seiki, Hiroyuki Aburatani, Sumiko Watanabe

Journal:

Journal of Neurochemistry

Year:

2010

Language:

english

File:

PDF, 1.20 MB

english, 2010

31

Membrane-type matrix metalloproteinases

Journal:

Year:

1999

Language:

english

File:

PDF, 795 KB

english, 1999

32

Tumor cell contact mediated transcriptional activation of the fibroblast matrix metalloproteinase-9 gene: involvement of multiple transcription factors including Ets and an alternating purine-pyrimidine repeat

Bruce P. Himelstein, Edward J. Lee, Hiroshi Sato, Motoharu Seiki, Ruth J. Muschel

Journal:

Clinical and Experimental Metastasis

Year:

1998

Language:

english

File:

PDF, 2.10 MB

english, 1998

33

Heat shock-mediated transient increase in intracellular 3′, 5′-cyclic AMP results in tumor specific suppression of membrane type 1-matrix metalloproteinase production and progelatinase A activation

Yasunobu Sawaji, Takashi Sato, Motoharu Seiki, Akira Ito

Journal:

Clinical and Experimental Metastasis

Year:

2000

Language:

english

File:

PDF, 143 KB

english, 2000

34

The proteolytic activity of MT4-MMP is required for its pro-angiogenic and pro-metastatic promoting effects

Lorin Host, Alexandra Paye, Benoit Detry, Silvia Blacher, Carine Munaut, Jean Michel Foidart, Motoharu Seiki, Nor Eddine Sounni, Agnès Noel

Journal:

International Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 1.73 MB

english, 2012

35

Matrix metalloproteinase expression and function during fin regeneration in zebrafish: Analysis of MT1-MMP, MMP2 and TIMP2

Shan Bai, Ryan Thummel, Alan R. Godwin, Hideaki Nagase, Yoshifumi Itoh, Li Li, Richard Evans, Jeffrey McDermott, Motoharu Seiki, Michael P. Sarras Jr.

Journal:

Year:

2005

Language:

english

File:

PDF, 6.35 MB

english, 2005

36

Nucleotide sequence of the protease-coding region in an infectious DNA of simian retrovirus (STLV) of the HTLV-I family

Jun-Ichiro Inoue, Toshiki Watanabe, Masako Sato, Akira Oda, Kumao Toyoshima, Mitsuaki Yoshida, Motoharu Seiki

Journal:

Year:

1986

Language:

english

File:

PDF, 3.27 MB

english, 1986

37

EXOSC9 depletion attenuates P-body formation, stress resistance, and tumorigenicity of cancer cells

Yoshino, Seiko, Matsui, Yusuke, Fukui, Yuya, Seki, Masahide, Yamaguchi, Kiyoshi, Kanamori, Akane, Saitoh, Yurika, Shimamura, Teppei, Suzuki, Yutaka, Furukawa, Yoichi, Kaneko, Shuichi, Seiki, Motoharu,

Journal:

Scientific Reports

Year:

2020

File:

PDF, 10.21 MB

2020

38

Membrane type 1 matrix metalloproteinase is a crucial promoter of synovial invasion in human rheumatoid arthritis

Mary-Clare Miller, Hugh B. Manning, Abhilash Jain, Linda Troeberg, Jayesh Dudhia, David Essex, Ann Sandison, Motoharu Seiki, Jagdeep Nanchahal, Hideaki Nagase, Yoshifumi Itoh

Journal:

Arthritis & Rheumatism

Year:

2009

Language:

english

File:

PDF, 782 KB

english, 2009

39

Comparison of autocrine mechanisms promoting motility in two metastatic cell lines: Human melanoma and ras-transfected NIH3T3 cells

Motoharu Seiki, Hiroshi Sato, Lance A. Liotta, Elliott Schiffmann

Journal:

International Journal of Cancer

Year:

1991

Language:

english

File:

PDF, 437 KB

english, 1991

40

Membrane-type 1 matrix metalloproteinase cytoplasmic tail binding protein-1 (MTCBP-1) acts as an eukaryotic aci-reductone dioxygenase (ARD) in the methionine salvage pathway

Wakako Hirano, Isamu Gotoh, Takamasa Uekita, Motoharu Seiki

Journal:

Year:

2005

Language:

english

File:

PDF, 322 KB

english, 2005

41

Structure of the region of the replication origin of the Bacillus subtilis chromosome

Seiki, Motoharu, Ogasawara, Naotake, Yoshikawa, Hiroshi

Journal:

Year:

1979

File:

PDF, 421 KB

1979

42

MT-MMPs play pivotal roles in cancer dissemination

Ikuo Yana, Motoharu Seiki

Journal:

Clinical and Experimental Metastasis

Year:

2002

Language:

english

File:

PDF, 298 KB

english, 2002

43

The U5 sequence is a cis-acting repressive element for genomic RNA expression of human T cell leukemia virus type I

Motoharu Seiki, Atsuko Hikikoshi, Mitsuaki Yoshida

Journal:

Year:

1990

Language:

english

File:

PDF, 852 KB

english, 1990

44

The protease MT4-MMP is essential for maintenance of vascular smooth muscle cell phenotype and vessel homeostasis in vivo

Mara M. Alonso, Motoharu Seiki, Alicia G. Arroyo

Journal:

Vascular Pharmacology

Year:

2012

Language:

english

File:

PDF, 54 KB

english, 2012

45

Transmembrane/Cytoplasmic Domain-Mediated Membrane Type 1-Matrix Metalloprotease Docking to Invadopodia is Required for Cell Invasion

Hirokazu Nakahara, Linda Howard, Erik W. Thompson, Hiroshi Sato, Motoharu Seiki, Yunyun Yeh and Wen-Tien Chen

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.69 MB

english, 1997

46

Two Cis-Acting Elements Responsible for Posttranscriptional Trans-Regulation of Gene Expression of Human T-Cell Leukemia Virus Type I

Motoharu Seiki, Jun-Ichiro Inoue, Makoto Hidaka and Mitsuaki Yoshida

Journal:

Proceedings of the National Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 1020 KB

english, 1988

47

Membrane-Type 4 Matrix Metalloproteinase (MT4-MMP) Modulates Water Homeostasis in Mice

Srichai, Manakan B., Colleta, Heloisa, Gewin, Leslie, Matrisian, Linsey, Abel, Ty W., Koshikawa, Naohiko, Seiki, Motoharu, Pozzi, Ambra, Harris, Raymond C., Zent, Roy, Uversky, Vladimir

Journal:

Year:

2011

Language:

english

File:

PDF, 2.01 MB

english, 2011

48

Inhibition of metastasis in human gastric cancer cells transfected with tissue inhibitor of metalloproteinase 1 gene in nude mice

Michio Watanabe, Yutaka Takahashi, Takahito Ohta, Masayashi Mai, Takuma Sasaki, Motoharu Seiki

Journal:

Year:

1996

Language:

english

File:

PDF, 511 KB

english, 1996

49

Ancorinosides B–D, inhibitors of membrane type 1 matrix metalloproteinase (MT1-MMP), from the marine sponge Penares sollasi Thiele

Masaki Fujita, Yoichi Nakao, Shigeki Matsunaga, Motoharu Seiki, Yoshifumi Itoh, Rob W.M van Soest, Nobuhiro Fusetani

Journal:

Year:

2001

Language:

english

File:

PDF, 124 KB

english, 2001

50

Isolation and structure elucidation of two phosphorylated sterol sulfates, MT1-MMP inhibitors from a marine sponge Cribrochalina sp.: revision of the structures of haplosamates A and B

Masaki Fujita, Yoichi Nakao, Shigeki Matsunaga, Motoharu Seiki, Yoshifumi Itoh, Rob W.M van Soest, Markus Heubes, D.John Faulkner, Nobuhiro Fusetani

Journal:

Year:

2001

Language:

english

File:

PDF, 220 KB

english, 2001

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